Tofacitinib is one of the newer medications approved by the fda for treatment of rheumatoid arthritis. In testimony before the food and drug administration, public citizen spoke against approval of the drug tolvaptan for use in polycystic kidney disease, citing its liver toxicity risks and that it does not meet essential elements of efficacy needed for drug approval. If you are thinking of using newly approved over-the-counter oxybutyin (oxytrol for women) to treat overactive bladder, find out why you should first check with your doctor and learn about possible adverse reactions.
Public citizen strongly opposes the food and drug administrations (fdas) approval of gabapentin for treatment of menopause-related vasomotor symptoms (vms, which includes hot flashes and flushing) due to the drugs questionable benefits and well-established risks. Food and drug administration, recently warned physicians and patients about safety concerns regarding two drugs commonly used to treat alzheimers disease. In this article, we review new research linking use of the heartburn and ulcer medications known as proton pump inhibitors to an increased risk of dementia.
Learn the facts about shingles and how you can lower your risk of developing it. Drug labels provide important information regarding the benefits and risks of prescription medications. The new recommended starting dose is more than a 2.
The article discusses the difference between the benefits of drugs to prevent a first fracture (primary prevention) and to prevent further fractures in people who have already experienced a fracture (secondary prevention). The article lists 35 different interacting drugs that can either increase blood levels of digoxin, leading to the serious problem of digitalis toxicity or decrease blood levels, causing the drug to be less effective. There is no evidence that this drug leads to substantial functional improvement or prevents the progression of the disease, and new evidence indicates that it may increase the risk of death.
Leflunomide (arava) was approved by the food and drug administration (fda) on september 10, 1998 to reduce signs and symptoms of active rheumatoid arthritis in adults and to retard structural damage as evidenced by x-ray erosion and joint space narrowing. Public citizen petitions the food and drug administration (fda) to add a black box warning regarding the risk of abortion to the amitizia product label, change the drugs pregnancy category from c to x, contraindicate nursing while taking the drug, require the distribution of an fda-approved medication guide for all patients, and mandate a dear doctor letter. Lyrica is heavily promoted for treatment of chronic pain due to fibromyalgia and other conditions.
Clearly, without evidence that teriparatide reduces fracture, the possibility of osteosarcoma outweighs any theoretical benefit of the drug. In december 2014, a federal grand jury in boston indicted 14 executives and employees of a massachusetts compounding pharmacy on 131 criminal charges in connection with a deadly nationwide fungal meningitis outbreak. The food and drug administration (fda) knew nearly five years ago about the dangers associated with the diabetes drug avandia, an internal fda memo shows. The salicylates are used to relieve pain and to reduce fever and inflammation. Regular readers of worst pills, best pills news will recognize the medical letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information.
In a recent complaint to the fda, we took several makers of diabetes drugs to task for direct-to-consumer ads that promote the drugs for unapproved uses. Dexmethylphenidate (focalin), approved by the food and drug administration (fda) in november 2001 for attention-deficithyperactivity disorder (adhd), joins a growing list of do not use drugs, so called because they primarily result in economic harm to both individuals and the health care system. There is no medical reason that you should be taking levocetirizine (xyzal) rather than one of the many other prescription and non-prescription antihistamines that are available in the market. Todays food and drug administration (fda) advisory committee vote confirms that the risks of propoxyphene (darvon) outweigh its benefits. Viagra accounts for more cases of a type of vision loss called ischemic optic neuropathy (ion) than any other drug (19 percent) and more than double the percentage of the next most often-reported drug.
However, after analyzing phase 2 and 3 pre-approval trials of alogliptin and post-marketing surveillance data for the drug from japan, the food and drug administration and european medicines agency concluded that the drugs potential hepatotoxicity warranted inclusion of warning language in the drugs label. Find out about 12 drugs that can interact with widely prescribed quetiapine -- 12 million prescriptions sold in 2010 -- to cause serious, sometimes fatal, heart arrhythmias. Fosamax (alendronate) or actonel (risedronate) the article discusses ways of preventing falls and other non-pharmacologic approaches to preventing fractures. Because of evidence from a number of studies, the food and drug administration (fda) recently required a black box label for all ssri (selective serotonin reuptake inhibitor) antidepressants indicating that use in children could lead to an increased risk of suicidal behavior. The article reviews evidence that one of the biggest-selling asthma drugs lacks evidence of a unique benefit and has been found to cause a variety of adverse psychiatric events, including nightmares, hallucinations and aggressiveness, especially in children.
This article provides information on how to minimize the risk when starting treatment with one of these products. Experts in the care of patients with hgh-related problems clearly state that giving hgh for antiaging, age management or bodybuilding is not medically appropriate particularly when weighing the potential benefits and risks. Learn about the problems of a common over-the-counter laxative, widely used for children but never approved for their use. If you or a family member experience the symptoms of potential liver toxicity listed in the article, contact the prescriber immediately. Shingles is a very common disease caused by the chicken (herpes zoster) virus. This purpose of this letter is to re-petition the fda to immediately ban the weight loss drug, sibutramine (meridia abbott in the u. The purposes of this letter are to petition fda to change the labeling and other sources of information about viagra to add important information about the drugs dangers currently missing from such sources and to warn doctors and patients that a substantial proportion of patients using the drug are unwittingly using it to treat impotence or other types of sexual dysfunction which are probably adverse reactions caused or worsened by other drugs known to impair sexual function. Yet another dietary supplement this one intended for weight reduction and body-building turns out to have life-threatening toxicity. The nerves which assist with this control can be found in the sympathetic trunk, which is several nerves that runs along side the spinal column. When tamoxifen, a known human carcinogen, is prescribed to healthy women, there must be compelling evidence of great benefit.Search Results for adverse effects of drugs. Proton-Pump Inhibitors: Dangerous and Habit-Forming Heartburn Drugs [hide all summaries] (September 2011)